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What does CBD do to the brain?

CBD (cannabidiol) has grown in popularity as a natural pain relief for the body, but what does CBD do to the brain?

the-brain icon 10
August 18, 2022
4 min read

CBD (cannabidiol) has grown in popularity in recent years, cropping up in everything from gummies to face creams. This seemingly magical compound is found in the cannabis plant and has been shown to have many health benefits. It's often used by people who are looking for natural pain relief for the body, but what does CBD do to the brain?

Let's start with what exactly this popular supplement is.

Article breakdown

What is CBD?

CBD is one of over 100 cannabinoids found naturally in the cannabis plant. Cannabinoids are a group of active compounds found in hemp plants and other plants. They are similar to endocannabinoids, which are produced naturally within the body. The endocannabinoid system (ECS) is involved in regulating many aspects of our health including sleep and mood.CBD can be used to help with pain relief, inflammation, anxiety, and even seizures.

Does CBD give you a mind high?

Firstly, it's important to note that CBD doesn't make you feel high. CBD is not a mind-altering drug. It doesn't produce the same effects as THC, which is the main psychoactive component of cannabis (marijuana). Now that's out the way, let's get on with discussing the question of how does CBD work in the brain.

What does CBD do to the brain?

CBD can help with anxiety and pain because it interacts with the CB1 and CB2 receptors in your brain. These receptors are part of our endocannabinoid system (ECS), which regulates homeostasis (the body's natural state).

The ECS is a network of receptors throughout the brain and body that respond to cannabinoids like CBD and helps regulate things like moods, appetite, sleep patterns, and pain sensitivity throughout the day. The ECS also plays a role in the regulation of memory formation and learning ability by helping reduce inflammation throughout your body.

Does CBD heal the brain?

The research on CBD and the brain are still new, so it's hard to pinpoint CBD long-term brain effects. That said, there have been promising findings on the healing effects of CBD.

Research shows that CBD could be helpful for preventing seizures, reducing inflammation, easing pain, helping sleep disorders, and improving mental health conditions (see studies at the bottom of the article). A common finding is its role in reducing anxiety symptoms, making it an effective way to manage stress or depression. As CBD can help to relieve inflammation and pain, this may be useful in healing brain diseases like multiple sclerosis. There are also some studies suggesting that CBD could be used as an anticonvulsant (controlling epilepsy).

Does CBD oil slow your brain down?

CBD doesn’t slow down your brain. People who use CBD don't experience any kind of “high” or mental fog when using CBD; in fact, many people say that their thinking becomes clearer after using it!

What are the side effects of CBD?

So what does CBD do to the brain that isn't so nice? Well, there's no evidence of physical addiction to CBD either, and there are no withdrawal symptoms if you suddenly stop taking it (unlike with nicotine and other substances). In fact, a 2011 review on the safety and side effects of CBD found that continuous use of the substance, even in extremely high doses like 1.500mg, had no negative consequences.

If side effects do occur, they're likely to be:

  • fatigue

  • diarrhea

  • change in appetite

that said, it's best to keep consumption moderate or low in general so that you don't experience any unwanted effects from too much of a good thing! To find the recommended dosage for your weight, age, and height, visit

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How does CBD affect the brain?

We know it can be confusing to figure out if CBD is right for you. But if you’re looking for a natural way to improve your health and well-being, you might find that CBD oil helps with chronic pain and anxiety, or even helps with sleep.

And if not? That’s okay too. There are other natural supplements that have a positive affect on your brain health. You might want to try The Smart Supplement - a unique formula of 20 clean, high-impact vitamins and minerals which target low energy, poor sleep, brain fog, and stress. We all have different bodies and brains, so find what works for you!

CBD Studies:




  • Smart Supplement
  • Braincare Journal
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