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Niacin (B3)

Read more about niacin (B3) and its importance for brain care.
Sophie Medlin
Head of Nutritional Research
April 13, 2020
2 min read

Major Functions

Converting food into energy - Cellular metabolism

In every dose

30mg (equal to 3 chicken breasts or 12 medium baked potatoes)

Fighting Talk

Deficiency in niacin can result in pellagra, a systemic disease which is characterised by brain fog, psychiatric symptoms and even dementia. It is currently in trials to test improvement in cognitive function and synaptic plasticity, which could help to keep the brain healthy in people with Alzheimer’s Disease.

What’s in it for my brain?

An antioxidant with an important role in cell signalling and DNA repair, Niacin is key for a normally functioning nervous system.

Fringe benefits

Essential for energy release 

Keeps skin healthy

Plays well with

B3 is available through diet, but mostly from animal sources, so those on a plant-based diet benefit from supplementation. To optimise the release of energy, it’s best consumed with other B vitamins.

Clever stuff

The brain requires niacin for the coenzymes NAD and NADP to get energy and function properly.


Evidence

Here’s a handful of relevant scientific studies on vitamin B3 (niacin).

  • Xu, X. J., & Jiang, G. S. (2015). Niacin-respondent subset of schizophrenia–a therapeutic review. Eur Rev Med Pharmacol Sci, 19(6), 988-997.
  • Wang, W., & Liang, B. (2012). Case report of mental disorder induced by niacin deficiency. Shanghai archives of psychiatry, 24(6), 352.
  • Kennedy, D. O. (2016). B vitamins and the brain: mechanisms, dose and efficacy—a review. Nutrients, 8(2), 68.
  • Gong, B., Pan, Y., Vempati, P., Zhao, W., Knable, L., Ho, L., ... & Pasinetti, G. M. (2013). Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer's mouse models. Neurobiology of aging, 34(6), 1581-1588.

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This product is not designed to replace a varied and balanced diet. Do not exceed stated dose. If you are pregnant, breastfeeding or taking any medication, please consult your doctor before use. Do not use it if the sachet has been opened. Store in a cool, dry place. Keep out of reach of children.