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Smart Supplement
Smart Supplement
Fuel for better living
Smart Probiotic
Smart Probiotic
Support for your microbiome
Ingredients
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Smart Probiotic

4.6/5 based on 178 reviews

Our high-impact formula, with 20bn CFUs of seven clinically studied strains, is the world’s first probiotic to support gut, brain, and immune health in one daily capsule.

1 per day
30 day supply
Improves digestion*
Reduces bloating*
Balances mood*
Free shipping in US/CA ∙ Pause & cancel any time
SPB - PDP HERO - #1
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30-day money-back
Vegan
Third-party tested
Non-GMO
No need to refrigerate
Gluten free
Russell Brand on the Smart Probiotic

“It helped my digestion and improved my mood in this miserable, rainy January in the northern hemisphere”.

RB video thumb

Gut health, redefined

Your gut is key to every aspect of health. Whether you have gut issues or not, microbiome disruption from modern lifestyles impacts our mental and physical health.

Our proprietary technology targets the gut-brain axis, delivering bacteria with proven benefits to the gut alive.

What to expect

Discover how the Smart Probiotic benefits you.

SPB — Benefits
Digestive health*

Supports digestion and growth of beneficial gut bacteria, while promoting regularity and stool hydration.

GI relief*

Helps alleviate GI discomfort, such as bloating, gas, constipation, and diarrhea.

Restores balance*

Aids intestinal barrier repair after antibiotics.

One capsule a day

All seven strains, along with zinc, are in every capsule.

At any time

We generally suggest taking it in the morning, but find a time that fits your schedule.

With or without food

No need to take anything else alongside your Smart Probiotic, unless you want to.

No need to refrigerate

Keep it in a cool, dark place.

World's most studied strains. Fact.

Designed by neuroscientists, dietitians, and gut experts over two years, the Smart Probiotic represents an unmatched commitment to research.

Our strains are backed by over 380 clinical studies, and we’re continuously investing in third-party testing.

Sophie – Experts
Sophie Medlin, RD
Head of Nutritional Research
Sophie Medlin, RD
Head of Nutritional Research
Consultant dietitian, chair of British Dietetic Association for London, founder of City Dietitians, spokesperson for evidence-based nutrition, and lecturer at King's College London.
Tara – Experts
Dr Tara Swart, PhD
Chief Science Officer
Dr Tara Swart, PhD
Chief Science Officer
Neuroscientist, medical doctor, leadership advisor, and MIT lecturer with a PhD in neuropharmacology.
SPB – Pill exploding

Designed to survive

Most probiotics don’t work—the bacteria die before they reach the gut.

But our delayed-release technology and proprietary protective matrix guarantee the majority of our 20bn CFUs reach your colon, where they can have an impact.

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Gut health

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Brain and mental health

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Immune health

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Gut health

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Brain and mental health

SPB_Gut_health_icon

Immune health

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Gut health

SPB_brain_health_icon

Brain and mental health

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Immune health

SPB – Quality – bottle in delivery box with hand

Engineered with precision

From strain-specific fermentation to continuous temperature checks, every stage of the Smart Probiotic’s manufacturing process is carefully monitored.

That’s why it contains 200x more live bacteria than best-selling over-the-counter alternatives.

We're here to help

Frequently asked questions

We’ve got the answers.

Find more answers on our FAQ page