The science
We’re committed to scientific rigour, investing in independent research and evidence-based development, so you can trust every capsule.

Real-life impact
Smart Probiotic
We ran an in vivo study to measure the impact of the Smart Probiotic. This eight-week, placebo-controlled trial studied the mood, microbiomes, and gut functions of 33 healthy participants.
The results
73% felt better mood
68% improved health overall
50% saw more microbial diversity
Reduced wind and bloating

Under the microscope
Smart Probiotic
We conducted an in vitro study with our independent lab partners ProDigest, who tested the efficacy of the Smart Probiotic using their SHIME® (Simulator of Human Intestinal Microbial Ecosystem) model.
The results
33.9bn CFUs reached colon alive
↑ butyrate production
↑ acetate production
↑ propionate production
Ingredient research
Independent studies that support the Smart Probiotic
Research on three of our favorite strains in the Smart Probiotic.
CEREBIOME®—B. longum Rosell®-175
Strength of evidence
Strong
Improves digestive health and relieves symptoms of gut discomfort.*
9
No. of studies
1987-2022
Years of studies
CEREBIOME®—L. helveticus Rosell®-52
Strength of evidence
Strong
Reduces stress and supports mental health and emotional balance.*
12
No. of studies
2011-2021
Years of studies
Saccharomyces boulardii
Strength of evidence
Strong
Enhances gut immune function while combating inflammation.*
8
No. of studies
2006-2019
Years of studies

Everyday effects
Smart Supplement
We wanted to document how the Smart Supplement affects people in their everyday lives. So, in partnership with Citrus Labs, we invested in a 12-week in vivo study of 32 healthy people to quantify its impact.
The results
75% felt better
55% improvement in recall
18% more focused
15% more sleep
Ingredient research
Independent studies that support the Smart Supplement
Research on three of our favorite nutrients in the Smart Supplement.
Omega 3 DHA
Strength of evidence
Strong
Improves cognitive function, including focus, learning, and memory.*
13
No. of studies
2010-2019
Years of studies
Vitamin D3
Strength of evidence
Strong
Promotes a positive mood, and may reduce the risk of anxiety and depression.*
9
No. of studies
2010-2019
Years of studies
Vitamin B12
Strength of evidence
Strong
Boosts energy, while at the same time reducing feelings of tiredness and fatigue.*
8
No. of studies
2008-2019
Years of studies
Developed by experts
Led by a team of acclaimed neurologists and dietitians, we review the latest research, investing in independent studies to ensure our products are always at the forefront of scientific progress.

Sophie Medlin, RD
Head of Nutritional Research
Sophie Medlin, RD
Head of Nutritional Research
Consultant dietitian, chair of British Dietetic Association for London, founder of City Dietitians, spokesperson for evidence-based nutrition, and lecturer at King's College London.

Dr Tara Swart, PhD
Chief Science Officer
Dr Tara Swart, PhD
Chief Science Officer
Neuroscientist, medical doctor, leadership advisor, and MIT lecturer with a PhD in neuropharmacology.