science magnesium

We follow the science

We’re committed to scientific rigour, investing in independent research and evidence-based development, so you can trust every capsule.

Vitals+

OUR CITRUSLABS STUDY

We partnered with Citruslabs in the USA to conduct a clinical study to measure how the Smart Supplement supports people in their everyday lives. We invested in a 12-week study of 32 healthy people to quantify its impact.

felt less stressed

felt less restless

felt less under pressure

felt overall better

Why it matters

We partnered with ProDigest to use their SHIME® (Simulator of the Human Intestinal Microbial Ecosystem) model. This replicates the exact conditions of the upper digestive tract so that we can map the journey of the Smart Probiotic on its way to the gut, ensuring the bacteria survive the harsh environment of the stomach.

increase mood
increase energy levels
increase mental clarity
increase sleep quality

Did you know?

High cortisol levels over weeks or months can lead to inflammation and a variety of mental and physical health issues like weight gain, high blood pressure, and an increased risk of diabetes.

Independent studies that support Vitals+

Strength of evidence: Strong

No. of studies: 13

Years of studies 2010 - 2019

Improves cognitive function, including focus, learning, and memory.*

See the science

Strength of evidence: Strong

No. of studies: 13

Years of studies 2010 - 2019

Improves cognitive function, including focus, learning, and memory.*

See the science

Strength of evidence: Strong

No. of studies: 13

Years of studies 2010 - 2019

Improves cognitive function, including focus, learning, and memory.*

See the science

Developed by scientists. Trusted by experts.

  • Sophie Medlin, RD Head of Nutritional Research

    Consultant dietitian, chair of British Dietetic Association for London, founder of City Dietitians, spokesperson for evidence-based nutrition, and lecturer at King’s College London.

    Sophie Medlin, RD Head of Nutritional Research
  • Dr. Tara Swart, PhD Chief Science Officer

    Consultant dietitian, chair of British Dietetic Association for London, founder of City Dietitians, spokesperson for evidence-based nutrition, and lecturer at King’s College London.

    Dr. Tara Swart, PhD Chief Science Officer

Our team of respected scientists and dietitians never stop working to bring you the results you want. So you can always trust that our supplements lead the way.

Meet our scientists

Frequently asked questions

Biotic⁺ is for everyone aged 12 and over, regardless of biological gender, including those on gluten-free, vegan, kosher, or halal diets.

If you’re pregnant or breastfeeding, or if you have any ongoing health problems, check with your doctor before starting any probiotic product.

For children under the age of 12, we recommend taking half the daily dose. You can do this by opening up the capsule and adding Biotic⁺ to some food, such as fruit or yogurt.

The probiotic strains won’t be protected by the delayed-release technology after opening the capsule. However, our acid-resistant strain selection and a proprietary protective matrix supports the survivability of strains even outside its capsule.

Good things take time (~3 months to be exact!). Your microbiome is as unique as your fingerprint, so everyone experiences changes at different times.

Biotic⁺ gets to work within the first 24-48 hours. You may feel some initial adjustment effects as your gut gets used to these new bacterial strains in your system. This is normal.

With daily use, these will subside in your first 1-3 weeks. The bacteria just need to acclimatise to their new environment. Longer term benefits, like normal heart, cognitive and immune function*, take a little longer.

The British Society of Gastroenterology recommend to anyone trying a new bacterial product to take it for at least 3 months, like Biotic⁺. This also mirrors our Third Party human (in vivo) study findings.

Don’t forget, a healthy gut is the source of everything.
*Zinc contributes to normal cognitive function. Zinc contributes to normal immune function. Zinc contributes to function of the heart and blood vessels.

Take one capsule a day, at any time of day, with or without food. Please don’t exceed the recommended dose.

Good news—you don’t need to keep Biotic⁺ in the fridge, as we use specially designed packaging to keep our strains stable.

We’ve carried out extensive testing to make sure each dose of Biotic⁺ will contain at least 20 billion CFUs for 18 months from the date of production, provided it is stored in a cool, dark place in its original packaging.

Our top tip: Keep Biotic⁺ on your bedside table, next to your coffee machine, or on your work desk, so you remember to take it every day.

Did you know that most of the symptoms blamed on probiotics (gas, bloating, indigestion) actually come from prebiotics?

And although prebiotics are an important part of any diet, you can’t fit enough into an easy-to-swallow capsule to make any difference at all?

So instead of including a worse-than-useless amount of prebiotics in Biotic⁺, we support a food-first approach to prebiotics, based an a varied diet with lots of vegetables.

We’ve designed Biotic⁺ and Vitals⁺ as the perfect combination of live bacteria and essential nutrients, specifically formulated to complement each other. From supporting absorption to fostering microbial diversity, when they work together, they’re even more effective.

Our ingredients

Our supplements are packed with the most effective ingredients out there, and nothing else.