Vitamin D3 Supplement Benefits and Dosage
Vitamin D3, aka the “sunshine vitamin" can lift your mood and support immunity, as well as build strong bones and teeth.
Vitamin D3, aka the “sunshine vitamin" can lift your mood and support immunity, as well as build strong bones and teeth.
Major functions of vitamin D3
A fat-soluble vitamin that is important for:
Preventing cognitive decline
Regulating the production of calcium and phosphate in bones
Bone growth and remodelling
Reducing inflammation
Regulating cell growth
Enhancing neuromuscular function
Supporting immune function
Helping with glucose metabolism
What is the Nutrient Reference Value (NRV—formerly RDA) of vitamin D3?
10 mcg/day (or 400 IU).
1 billion people in the world are suffering from vitamin D deficiency.
Researchers have now concluded that we need more vitamin D than is currently recommended for overall health and to prevent chronic diseases.
Granted, your body makes vitamin D when those golden rays of sunshine fall on your skin, and also when you eat certain foods, but it’s not always enough. Moreover, coronavirus (SARS-CoV-2) has forced people to spend more time indoors, so Public Health England (PHE) has asked everyone (not just at-risk groups) to consider taking a daily vitamin D supplement.
In every Smart Supplement dose
20 mcg (800 IU) – that’s the equivalent of 20 eggs or 13 tablespoons of fortified margarine*
(*Ain’t nobody got time for that)
Benefits of vitamin D3 on the brain
Vitamin D3 is a nutritional superhero that helps to prevent cognitive decline, as well as playing an important role in immune function. It’s involved in many brain processes including neuro-immunomodulation (a fancy way of saying that it regulates the production of compounds in your brain that can boost your immune system).
Receptors for vitamin D3 (and the enzyme that converts it into its active form) are present in the parts of your brain that control cognitive function as you age. When vitamin D3 attaches to these receptors, it can inhibit an enzyme involved in the development of Alzheimer’s and Parkinson’s disease. In one study, vitamin D concentrations were lower in patients with dementia than those without.
In two other studies, people with vitamin D deficiency had higher rates of mood disorders, depression, and low mood. Although vitamin D is not recommended as a first-line treatment for depression, it may be beneficial in combination with therapy.
One study showed that vitamin D supplementation may also help with decreasing the risks of developing multiple sclerosis (MS) by influencing how the immune system works. However, more research is needed to find out how much vitamin D supplementation is necessary to decrease MS risks.
Benefits of vitamin D3 on the body
Vitamin D3 does so much more than give you strong bones and teeth. Here are some evidence-based benefits of vitamin D3 on the body:
Promotes healthy bones, teeth, and muscles.
Enhances the body’s immune system.
Decreases the multiplication of cancerous cells, and prevents the formation of new blood vessels and inflammation.
Protects the heart by reducing inflammation (low vitamin D3 has been linked to a higher risk of heart disease).
Regulates sodium concentrations through the renin-angiotensin system, which decreases the risk of hypertension.
Low vitamin D has been linked to obesity, type 2 diabetes, depression, auto-immune diseases, influenza, bacterial vaginosis, and age-related macular degeneration in women.
Why vitamin D is important for the ageing population
As you get older, the cells in your skin make less vitamin D from sunlight (cutaneous synthesis). Also, you may begin to spend less time outdoors and eat less of foods that are fortified with vitamin D.
This means that ageing adults are at risk of vitamin D deficiency. It also means that vitamin D may also influence some age-related medical conditions. It’s important that older adults aged 60 years and over consider taking a vitamin D supplement.
Clever stuff
Vitamin D comes in two forms: ergocalciferol (vitamin D2) and cholecalciferol (vitamin D3). Vitamin D3 is the biologically-active form and is the more powerful of the two, increasing blood levels of vitamin D twice as much as D2.
Vitamin D3 deficiency symptoms
Since 35% of total vitamin D intake from food is from meat and meat products (including fish), vegetarians need to get creative with supplementing their diet with vitamin D3. People who can’t tolerate or consume milk and eggs are also at higher risk of vitamin D3 deficiency.
Insufficient amounts of D3 can prevent normal bone development and bone growth. It can also cause mood disorders, depression, and low mood.
Signs of Vitamin D3 deficiency include:
Fatigue
Bone pain
Muscle weakness, muscle aches, or muscle cramps
Mood changes, for example, depression
Diseases from prolonged vitamin D deficiency:
Rickets—bone tissues do not harden, which can cause soft bones and skeletal deformities in children
Osteopenia—bone tissues are weaker than normal, but not to the point of breaking easily
Osteoporosis—bone tissues are weak and brittle, increasing your risk of falls and fractures
Osteomalacia—weak and soft bones in adults
Muscle weakness—difficulty standing and walking in children; increased loss of balance and more frequent falls in the elderly
Food sources of vitamin D3
Most vitamin D3 comes from exposure to sunlight. However, eating the following foods also provides the body with some vitamin D3.
Salmon
Trout
Tuna
Swordfish
Sturgeon
Cod liver oil
Meat and meat products
Fortified milk and milk products
Fortified cereal and cereal products – about 13-20% of the total dietary intake of vitamin D in the UK population comes from these products
Fortified orange juice
Mushrooms
Eggs, hard-boiled
Vitamin D3 side effects
Too much vitamin D3 (more than 100 mcg/day) from supplements over time can be toxic. Since vitamin D3 helps with calcium absorption, too much of it can lead to excess calcium (hypercalcemia).
Excess calcium can cause weak bones, muscle weakness, kidney stones, heart problems, or changes in how your brain works (for example, confusion, moodiness, or fatigue).
Don’t worry about vitamin D3 overdose from sunlight. Our body is brilliant at regulating the amount of vitamin D you get from the sun, so there’s no risk of ending up with too much. How we use vitamin D3 in Heights’ Smart Supplement
Unless you consume your vitamins in conjunction with a fat, your body can’t absorb them. This is why we wrap vitamin D3 (and other fat-soluble vitamins like E and A) in omega 3 extracted from algae oil to make sure that your body can absorb it.
Evidence
Trang, H. M., Cole, D. E., Rubin, L. A., Pierratos, A., Siu, S., & Vieth, R. (1998). Evidence that vitamin D3 increases serum 25-hydroxyvitamin D more efficiently than does vitamin D2. The American journal of clinical nutrition, 68(4), 854-858.
Allan, G. M., Cranston, L., Lindblad, A., McCormack, J., Kolber, M. R., Garrison, S., & Korownyk, C. (2016). Vitamin D: a narrative review examining the evidence for ten beliefs. Journal of general internal medicine, 31(7), 780-791.
Vellekkatt, F., & Menon, V. (2019). Efficacy of vitamin D supplementation in major depression: A meta-analysis of randomized controlled trials. Journal of postgraduate medicine, 65(2), 74.
National Institutes of Health. (2014). Office of Dietary Supplements, Vitamin D Fact Sheet for Health Professionals.
Vaziri, F., Nasiri, S., Tavana, Z., Dabbaghmanesh, M. H., Sharif, F., & Jafari, P. (2016). A randomized controlled trial of vitamin D supplementation on perinatal depression: in Iranian pregnant mothers. BMC pregnancy and childbirth, 16(1), 1-12.
2015-2020 Dietary Guidelines | health.gov. Accessed January 21, 2021. https://health.gov/our-work/food-nutrition/previous-dietary-guidelines/2015
SACN vitamin D and health report. GOV.UK. Accessed January 21, 2021. https://www.gov.uk/government/publications/sacn-vitamin-d-and-health-report
Statement from PHE and NICE on vitamin D supplementation during winter. GOV.UK. Accessed January 21, 2021. https://www.gov.uk/government/publications/vitamin-d-supplementation-during-winter-phe-and-nice-statement/statement-from-phe-and-nice-on-vitamin-d-supplementation-during-winter
Meehan M, Penckofer S. The Role of Vitamin D in the Aging Adult. J Aging Gerontol. 2014;2(2):60-71. doi:10.12974/2309-6128.2014.02.02.1
Penckofer S, Kouba J, Byrn M, Ferrans CE. Vitamin D and Depression: Where is all the Sunshine? Issues Ment Health Nurs. 2010;31(6):385-393. doi:10.3109/01612840903437657
Sintzel MB, Rametta M, Reder AT. Vitamin D and Multiple Sclerosis: A Comprehensive Review. Neurol Ther. 2017;7(1):59-85. doi:10.1007/s40120-017-0086-4
Buell JS, Dawson-Hughes B. Vitamin D and Neurocognitive Dysfunction: Preventing “D”ecline? Mol Aspects Med. 2008;29(6):415-422. doi:10.1016/j.mam.2008.05.001
Wilkins CH, Sheline YI, Roe CM, Birge SJ, Morris JC. Vitamin D deficiency is associated with low mood and worse cognitive performance in older adults. Am J Geriatr Psychiatry. 2006;14(12):1032-1040. doi:10.1097/01.JGP.0000240986.74642.7c
Naeem Z. Vitamin D Deficiency- An Ignored Epidemic. Int J Health Sci (Qassim). 2010;4(1):V-VI.
Vitamin D Deficiency: Symptoms & Treatment. Accessed January 21, 2021. https://my.clevelandclinic.org/health/articles/15050-vitamin-d--vitamin-d-deficiency
Vitamin D recommendations | International Osteoporosis Foundation. Accessed January 21, 2021. https://www.osteoporosis.foundation/vitamin-d-recommendations
Calame W, Street L, Hulshof T. Vitamin D Serum Levels in the UK Population, including a Mathematical Approach to Evaluate the Impact of Vitamin D Fortified Ready-to-Eat Breakfast Cereals: Application of the NDNS Database. Nutrients. 2020;12(6). doi:10.3390/nu12061868
Vitamin D toxicity: What if you get too much? Mayo Clinic. Accessed January 21, 2021. https://www.mayoclinic.org/healthy-lifestyle/nutrition-and-healthy-eating/expert-answers/vitamin-d-toxicity/faq-20058108
Fernandes de Abreu DA, Eyles D, Féron F. Vitamin D, a neuro-immunomodulator: implications for neurodegenerative and autoimmune diseases. Psychoneuroendocrinology. 2009;34 Suppl 1:S265-277. doi:10.1016/j.psyneuen.2009.05.023
Nair R, Maseeh A. Vitamin D: The “sunshine” vitamin. J Pharmacol Pharmacother. 2012;3(2):118-126. doi:10.4103/0976-500X.95506